Our recent research focuses on the rational design of water-soluble, long-wavelength emissive aggregation-induced emission (AIE/rAIE) luminogens for advanced biosensing and theranostic applications. By engineering donor–π–acceptor frameworks and tuning charge exposure, we develop smart fluorophores capable of ultrasensitive, selective detection of clinically relevant biomacromolecules in complex pseudo-physiological media. A parallel emphasis is placed on visible-light-activated photosensitizers that generate hybrid reactive oxygen species for image-guided photodynamic therapy, enabling integrated diagnosis and treatment under biocompatible conditions.

Development of novel, efficient, and sustainable synthetic methodologies in organic chemistry, with a strong emphasis on heterocyclic framework construction.

Design of multistep, cascade, and metal-free synthetic strategies for the rapid assembly of complex and functionally diverse molecular architectures.

Exploration of new reaction mechanisms and synthetic transformations to improve atom economy, selectivity, and overall synthetic efficiency.

Synthesis and functionalization of heterocyclic systems relevant to medicinal chemistry and advanced functional materials.

Research in supramolecular chemistry and molecular recognition, focusing on selective ion and neutral molecule binding.

Design of BODIPY-modulated heterocyclic systems for ion sensing, photophysical studies, and structure–property correlations.

Development of supramolecular organogels and soft functional materials for applications in sensing, medicinal chemistry, and environmental remediation.